Jose Rodriguez

Biography

Born in Aguascalientes, Mexico; raised in Los Angeles, Jose is a Bruin class of 2007 (B.S.), 2012 (Ph.D.) and an assistant Professor of Chemistry & Biochemistry at UCLA.

Research

Jose leads a group focused on molecular structure determination within the Department of Chemistry & Biochemistry at UCLA.

Selected Publications

Gallagher-Jones, M., Bustillo, K.C., Ophus, C., Richards, L.S., Ciston, J., Lee, S., Minor, A.M., Rodriguez, J.A. (2020) Atomic structures determined from digitally defined nanocrystalline regions. IUCrJ 7(3).

Jones, C.G., Asay, M., Kim, L.J., Kleinsasser, J.F., Saha, A., Fulton, T.J., Berkley, K.R., Cascio, D., Malyutin, A.G., Conley, M.P., Stoltz, B.M., Lavallo, V., Rodriguez, J.A., Nelson, H.M. (2019) Characterization of Reactive Organometallic Species via MicroED. ACS Central Sci. DOI: 10.1021/acscentsci.9b00403

Zee C., Glynn C., Gallagher-Jones M., Miao J., Santiago CG., Cascio D., Gonen T., Sawaya MR. and Rodriguez JA. (2019) Homochiral and racemic MicroED structures of a peptide from the ice nucleation protein InaZ. IUCrJ. 6(Pt 2):197-205.

Jones, C.G., Martynowycz, M.W., Hattne, J., Fulton, T.J., Stoltz, B.M., Rodriguez, J.A., Nelson, H. and Gonen, T. (2018) The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination. ACS Central Sci. 4 (11), 1587–1592.

Gallagher-Jones M., Ophus C., Bustillo KC., Boyer DR., Panova O., Glynn C., Zee C., Ciston J., Mancia KC., Minor AM., and Rodriguez JA. (2019) Nanoscale mosaicity revealed in peptide microcrystals by scanning electron nanodiffraction. Nat. Comms. Biol. 2:26.

Gallagher-Jones, M., Baraldi-Dias, C.S., Pryor, A.J., Bouchmella, K., Zhao, L., Lo, Y.H., Cardoso, M.B., Shapiro, D., Rodriguez, J., Miao, J. (2017) Correlative cellular ptychography with functionalized nanoparticles at the Fe L-edge. Nat. Sci. Reports. 7: 4757.

Colletier, J.P., Sawaya, M.R., Gingery, M., Rodriguez, J.A., Cascio, D., Brewster, A.S., Boutet, S., Williams, G.J., Messerschmidt, M., DePonte, D.P., Sierra, R.G., Laksmono, H., Koglin, J., Hunter, M.S., Park, H.W., Uervirojnangkoorn, M., Bideshi, D.K., Brunger, A.T., Federici, B.A., Sauter, N.K., Eisenberg, D.S. (2016) A potent mosquito larvicide revealed by de novo phasing with an X-ray free-electron laser. Nature. DOI 10.1038/nature19825.

Glynn, C., Sawaya, M.R., Ge P., Gallagher-Jones, M., Short, C.W., Bowman, R., Apostol, M., Zhou, Z.H., Eisenberg, D.S., Rodriguez, J.A. (2020) Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core. Nature SMB. doi: 10.1038/s41594-020-0403-y.

Gallagher-Jones, M., Glynn, C., Boyer, D.R., Martynowycz, M.W., Hernandez, E., Miao, J., Zee, C., Novikova, I.V., Goldschmidt, L., McFarlane, H.T., Helguera, G.F., Evans, J.E., Sawaya, M.R., Cascio, D., Eisenberg, D.S., Gonen, T. and Rodriguez, J.A. (2018) Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp. NSMB. 25, 131-134.

Rodriguez, J.A., Magdalena, I., Sawaya, M.R., Cascio, D., Reyes, F., Shi, D., Guenther, E., Johnson, L., Hattne, J., Sangwan, S., Nannega, B., Brewster, A.S., Messerschmidt, M., Boutet, S., Sauter, N.K., Gonen, T., and Eisenberg, D. (2015) Structure of the toxic core of alpha-synuclein from invisible crystals. Nature. 525(7570):486-90.